By Shoib Ahmad Baba, Nasheeman Ashraf
This ebook is a made of years of analysis on saffron biology. It intends to provide a wide yet concise evaluation of many of the facets of apocarotenoid biosynthesis in Crocus sativus, its legislation and pharmacology .
Crocus sativusL. of kin Iridaceae is a vital medicinal plant. The dried stigma of C. sativus flower is taken into account because the world's most expensive spice. Saffron is the resources of distinctive carotenoid derived molecules known as apocarotenoids which come with crocin, crocetin, picrocrocin and safranal. those molecules are synthesized within the tissue and developmental degree particular demeanour. in addition to supplying color, aroma and flavour to the spice, those molecules have great medicinal value.
The ebook uncovers significant suggestions of apocarotenoids biosynthesis and offers deeper and extra whole knowing approximately their biotechnological and pharmacological applications.
The e-book is split into 3 sections –
The first part offers a basic creation of C. sativus, its apocarotenoids, their biosynthesis, legislation and delivery. moment part offers information regarding the carotenoid cleavage dioxygenases (CCDs) that are the major avid gamers in apocarotenoid biosynthesis. The class of plant CCDs, their constitution, response mechanism, biotechnological program are completely mentioned. the ultimate part bargains with the key pharmacological homes of C. sativus apocarotenoids, starting from their function as anticancer to their application as neuroprotective molecules.
This is a considered one of its sort e-book on Crocus sativus. It should be important for the researchers operating on Crocus sativus, students and in addition practitioners desirous about extraction and bio-synthesis of the priceless clinical components.
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Additional resources for Apocarotenoids of Crocus sativus L: From biosynthesis to pharmacology
Konoshima et al. 4 Cardioprotection 47 (Konoshima et al. 1998).
J plant physiol 189:114–125 Baba SA, Mohiuddin T, Basu S, Swarnkar MK, Malik AH, Wani ZA, Abbas N, Singh AK, Ashraf N (2015c) Comprehensive transcriptome analysis of Crocus sativus for discovery and expression of genes involved in apocarotenoid biosynthesis. BMC Genomics 16(1):1 Bouvier F, Suire C, Mutterer J, Camara B (2003) Oxidative remodeling of chromoplast carotenoids identification of the carotenoid dioxygenase CsCCD and CsZCD genes involved in Crocus secondary metabolite biogenesis. Plant Cell 15(1):47–62 Bouvier F, Isner JC, Dogbo O, Camara B (2005a) Oxidative tailoring of carotenoids: a prospect towards novel functions in plants.
Crocins present in C. sativus are powerful free radical quenchers and have been used in traditional medicine since thousands of years. They display a variety of health benefits and have gained attention due to their sedative, analgesic, and anticancer properties (Zhang et al. 2009). However, limited availability of crocins forms a bottleneck in commercial utilization of crocins from saffron and results in the in prohibitive market prices. Principally, Crocus apocarotenoids including crocin are synthesized by the oxidative cleavage of either zeaxanthin or β-carotene by CCDs.
Apocarotenoids of Crocus sativus L: From biosynthesis to pharmacology by Shoib Ahmad Baba, Nasheeman Ashraf