By M. Kowalski
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Additional resources for Allergic Rhinitis
2002) SLIT with grass pollen extracts was shown to decrease local or systemic levels of eosinophil cationic protein (ECP), without any increase in tryptase. , 2001). Clinical Implications and Facts About Allergic Rhinitis (AR) in Children 23 Changes in the pattern of allergen specific T-cell responses. Recent studies focused on the impact of SLIT on CD4+ T cells responses. It is well known that allergic patients usually mount strong allergen-specific Th2 cells immune response, characterized by the secretion of high amounts of interleukin IL-4, IL-5 and IL-13 cytokines.
Nasal symptoms are associated with school performance in adolescents. J Adolesc Health. 2007; 40:581–583. Taylor A, Verhagen J, Akdis CA, Akdis M. T regulatory cells in allergy and health: a question of allergen specificity and balance. Int Arch Allergy Immunol 2004;135:73– 82. Torres Lima M, Wilson D, Pitkin L, Roberts A, Nouri-Aria K, Jacobson M et al. Grass pollen sublingual immunotherapy for seasonal rhinoconjunctivitis: a randomized controlled trial. Clin Exp Allergy 2002; 32:507–514. 32 Allergic Rhinitis Valovirta E, Jacobsen L, Ljorring C, Koivikko A, Savolainen J.
Tr1 cells, Th3 cells, and CD8+ regulatory T cells). There is a growing evidence supporting the role of regulatory T cells in controlling the development of asthma and allergic disease in a variety of models , although it is not clear yet which of the various regulatory T cell subsets are the most important in this regard. , 2004) A revised version of the hygiene hypothesis proposes that a limited exposure to infectious pathogens during infancy, most particularly telluric mycobacteria and parasites, may prevent the establishment of not only a Th1, but also a T reg repertoire, thereby explaining in part the observed increase in prevalence of allergies in developed countries.
Allergic Rhinitis by M. Kowalski