By James L Bittle; Frederick A Murphy
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Additional resources for Advances in veterinary science and comparative medicine. Vol. 33, Vaccine biotechnology
The effects of this virus are relatively mild in older animals. 36 J A M E S L. BITTLE A N D S U S I E M U I R Immunization. Attenuated live-virus vaccines administered parenterally to pregnant swine in the latter part of the gestation period produce colostral antibodies. Apparently, in sows previously exposed to TGE, this vaccine produces sufficient immune responsiveness to be of value. The vaccine is also used orally in pigs 1-3 days old to induce local immunity. The effectiveness of this use of the vaccine has not been thoroughly demonstrated.
These are highly efficacious vaccines and are routinely used in veterinary medicine. E. Mycobacterium Although infections with Mycobacterium tuberculosis primarily occur through inhalation of the tubercle bacillus, ingestion of large numbers of the bacilli in contaminated milk or infectious sputum can readily produce disease in susceptible species. The bacterium is pathogenic in man, but can also cause disease in monkeys, pigs, and occasionally in cattle, dogs, and parrots. The disease may be asymptomatic or produce severe, debilitating pulmonary lesions.
Transmissible Gastroenteritis Virus (TGE) TGE is an often fatal disease of pigs under 2 weeks of age. The main lesion is enteritis, resulting in malabsorption, diarrhea, and dehydration. TGE virus is serologically related to FIP virus, but the diseases have entirely different characteristics. There is one serotype of TGE virus and one serotype of FIP virus. High levels of maternal TGE antibody in sows' colostrum protect piglets if fed continuously. Immunity of this type has been produced by feeding sows tissues containing virulent TGE virus several weeks prior to gestation.
Advances in veterinary science and comparative medicine. Vol. 33, Vaccine biotechnology by James L Bittle; Frederick A Murphy